Th2 cell clonal anergy as a consequence of partial activation.

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Th2 cell clonal anergy as a consequence of partial activation

We have demonstrated Th2 clonal anergy as a consequence of partial T cell activation by immunogenic peptide and chemically fixed APC, as well as by altered peptide ligand and live antigen-presenting cells (APC). Either stimulation resulted in a profound inability of the T cells to proliferate upon restimulation with antigen and functional APC, a similar phenomenon to that found with Th1 cells. ...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1994

ISSN: 0022-1007,1540-9538

DOI: 10.1084/jem.180.4.1195